Latest advancement in Granulation technology and its future
Pharmaceutical manufacturing technology has gone through a whole lot of changes over the last 5 to 6 decades, especially since the end of World War II. Until the late fifties, pharmaceutical manufacturing technology involved mixing and blending equipment that basically...
Hot Melt Extrusion Process in Pharmaceutical Drug Formulation
Introduction: Formulators rely on science and technology knowledge for solutions to new or existing problems through well-considered combinations of methodologies and approaches that profoundly impact the healthcare and pharmaceutical industry. They understand and evaluate the pre-formulation phase, formulation and process...
Decoding Evaluation Methods of Pharmaceutical Pelletization
Pharmaceutical Pellets are small, free-flowing, spherical particulates manufactured by the agglomeration of a fine powder, granules of drug substances and excipients using appropriate processing equipment. Pelletization and Granulation are often used interchangeably. However, pelletization technique is considered superior to most...
A Guide to Isolator Gloves
"Pickles". Yes, I am referring to the undisputed favourite accompaniment to Indian food cuisine. A few weeks back, I was observing my mother making some lip-smacking mango pickles. However, my focus shifted from the recipe to the process. The striking...
Granulation: An Important Process in Tablet Manufacturing
Non-Sterile Oral Solids mainly refer to the following, namely Tablets Capsules and Powders and Granules. As a continuation of the Granulation 101 blog , this article touches upon the importance of the granulation process. Manufacturing of tablets by the direct...
Our tips on selecting the right containment system for pharma
Prevention of cross-contamination with highly potent active pharmaceutical ingredients (HPAPI) is a crucial part of a safe manufacturing process. Similarly, it is essential for APIs or finished drug products manufacturing companies to ensure the safety of workers and the environment...
A Beginner’s Guide to Pharmaceutical Coating
Medications have transformed from "only" medicinal ingredients during ancient Egpyt to acquiring various shapes, sizes, i.e. tablets, capsules and syrups in modern times. Also, it was not until the mid-twentieth century that colours became an essential addition to the coating...
Granulation techniques
As I explained in my previous post, the process through which primary powder particles adhere to form larger multi-particle entities is known as granulation. In this post, I explain various granulation techniques. Granulation is a step in the preparation of...