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Process

Prefilled Syringe – The Smart Spike

As I write this blog, it is quite likely that a transformation is taking place somewhere. This change could be small or, at other times, so big that it can lead to a huge impact all around. And the past...
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Process

Pass Box Qualification – Ticking all the right boxes

I vividly remember the day when I was introduced to the world of a cleanroom. I was pretty much cognizant of the functioning and essence of a cleanroom until I was handed over a comprehensive manual that discussed each component...
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Process

GAINFUL GRANULATION vs CORRECT COMPRESSION – understanding the easy way

The role of granulation in tablet manufacturing is indisputable. The formation of granules, if characterized optimally, enhances the uniformity of the API, and has significant impact on the tablet's flowability and compressibility. As we all know, several manufacturing unit operations...
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Process

Beta Carotene Microspheres – Laboratory Trial

Derived from the word ‘Beta’ and ‘Carrot’, ‘Beta Carotene’, is a plant pigment found in carrots. Beta Carotene while entering our body gets converted into Vitamin A which is an essential micronutrient. It helps one maintain good vision, lining of...
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Process

Pharmaceutical Product Development – in Perspective and Practice

The following discussion is primarily in the context of development of expired Generic or Patent pharmaceutical dosage forms, which can be pharmaceutically and bio pharmaceutically equivalent to an established international brand leader (Innovator). However, it is neither intended nor should...
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Process

Fabtech’s Think Tank – Making It Possible

Back during the World War II, several military jargons came to be used in discussions on strategic planning and execution. In tune with the ongoing wars all around, the top decision making authorities then began to be referred to as...
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Process

High Shear Granulations (HSG) Vs Fluid Bed Granulations (FBG) – A...

Granulation that forms the core component of the pharmaceutical industry continues to grow with improved technologies and accelerated advancement.  Apparently, High Shear Granulation (HSG) technique that offers an enhanced shaping process has been widely accepted as the optimum choice of...
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Process

Meeting challenges through technology (Commercial-Scale Product Trials)

Even as the severity of the pandemic continues to hound us now and then, a few thumb rules always need to be adhered to until the pandemic is completely wiped out. Amidst the masks, sanitizers and frequent hand washing, there...
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Process

Properties of a good tablet granulation

What are the ideal properties of a good tablet granulation? Again a very loaded question but a very frequently asked question too. Let us try to identify the ideal properties and try to give them some usable numbers and figures. The...
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Process

The trial at Application Service Centre Part-2

This blog is a continuation of the Tech trial series Part-I where we talked about the development of NPS sugar beads from sugar powder using Fluid Bed Columns for one of our customers. In this series, we take our trial...
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