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Pharmaceuticals

A Beginner’s Guide to Pharmaceutical Coating

Medications have transformed from "only" medicinal ingredients during ancient Egpyt to acquiring various shapes, sizes, i.e. tablets, capsules and syrups in modern times. Also, it was not until the mid-twentieth century that colours became an essential addition to the coating...
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Granulation Techniques - Fluid Bed Processor, Single Pot Granulator

Pharmaceuticals

Granulation techniques

As I explained in my previous post, the process through which primary powder particles adhere to form larger multi-particle entities is known as granulation. In this post, I explain various granulation techniques. Granulation is a step in the preparation of...
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Air

The advantages of modular over traditional construction for pharmaceutical...

ISO standard 14644-1 defines a cleanroom as "a room in which the concentration of airborne particles is controlled, and which is constructed and used in a manner to minimise the introduction, generation, and retention of particles inside the room and...
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OEB 5 isolator for oncological product

Containment Solutions

Any challenge can be overcome with clarity, focus and a committed team

A little over a year ago, a potential customer based in Maghreb reached out to us. They wanted an R&D scale manufacturing system for an OEB 5 oncological product. We sat down with them to understand their needs and probed...
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Granulation and Single Pot Processor

Pharmaceuticals

Granulation 101 – The basics

Tablets and capsules continue to be the most commonly manufactured oral solid dosage form in the pharmaceutical industry. Before tabletting, pharmaceutical compounds undergo granulation to improve flowability and processing. 'Granulation is the process of collecting particles together by creating bonds...
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Time management results in on-time deliveries always

Life Engineering

Time Management: Getting the timing right!

Googling 'time management' throws up about 5 billion results. There are countless books, blogs, infographics, how-to videos, all sharing their tips on effective time management. There are even consultants who help you manage your time better. Despite all these reams...
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Static & Dynamic Pass Boxes for Cleanrooms

Air

Key differences between static and dynamic pass boxes

In a pharmaceutical manufacturing facility where a sterile environment is paramount, equal importance must be given to ensuring the movement of materials does not compromise the sanctity of the cleanroom. Operators account for the largest single source of contamination in...
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Air

Common cleanroom hazards you should know about

While cleanrooms are supposed to be the quintessential sterile space, there is no guarantee of a perfect, contaminant free cleanroom. However risk of contamination can be minimised by adhering to proper protocols including room pressure requirements, proper gowning procedures. While...
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Air

The benefits of intertwined circuiting in split coils

In my earlier post on Treated Fresh Air technology, I spoke about how the HVAC sector is continually evolving as new technologies develop and new concepts come into play. As most of these technologies and innovations are relatively unknown, we...
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Air

The increasingly important role of RABS in aseptic filling operations

There are multiple potential sources of contamination in any cleanroom environment, from the transfer of materials to the incoming air system. Even in a well-designed and operated cleanroom set up, operators present one of the primary sources of incoming contamination....
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We are a world leader delivering start-to-finish (turnkey) engineering solutions for pharmaceutical, biotech and healthcare companies all over the world. We are trusted by over 1000 customers in 53 countries. Our mission is to make medicines affordable and accessible everywhere by building pharmaceutical and healthcare capability.

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