A Beginner’s Guide to Pharmaceutical Coating
Medications have transformed from "only" medicinal ingredients during ancient Egpyt to acquiring various shapes, sizes, i.e. tablets, capsules and syrups in modern times. Also, it was not until the mid-twentieth century that colours became an essential addition to the coating...
Granulation techniques
As I explained in my previous post, the process through which primary powder particles adhere to form larger multi-particle entities is known as granulation. In this post, I explain various granulation techniques. Granulation is a step in the preparation of...
The advantages of modular over traditional construction for pharmaceutical...
ISO standard 14644-1 defines a cleanroom as "a room in which the concentration of airborne particles is controlled, and which is constructed and used in a manner to minimise the introduction, generation, and retention of particles inside the room and...
Any challenge can be overcome with clarity, focus and a committed team
A little over a year ago, a potential customer based in Maghreb reached out to us. They wanted an R&D scale manufacturing system for an OEB 5 oncological product. We sat down with them to understand their needs and probed...
Granulation 101 – The basics
Tablets and capsules continue to be the most commonly manufactured oral solid dosage form in the pharmaceutical industry. Before tabletting, pharmaceutical compounds undergo granulation to improve flowability and processing. 'Granulation is the process of collecting particles together by creating bonds...
Time Management: Getting the timing right!
Googling 'time management' throws up about 5 billion results. There are countless books, blogs, infographics, how-to videos, all sharing their tips on effective time management. There are even consultants who help you manage your time better. Despite all these reams...
Key differences between static and dynamic pass boxes
In a pharmaceutical manufacturing facility where a sterile environment is paramount, equal importance must be given to ensuring the movement of materials does not compromise the sanctity of the cleanroom. Operators account for the largest single source of contamination in...
Common cleanroom hazards you should know about
While cleanrooms are supposed to be the quintessential sterile space, there is no guarantee of a perfect, contaminant free cleanroom. However risk of contamination can be minimised by adhering to proper protocols including room pressure requirements, proper gowning procedures. While...